Holiste conducts multidisciplinary research in order to deepen knowledge on the mechanisms of cellular oxygenation and study new applications. This integrates explorations in the fields of physics, chemistry and molecular biology, in partnership with researchers, academics and medical professors. New observations, theses and publications regularly confirm the importance of this method of natural oxygenation, without risk of free radicals.

Bol d'air Jacquier

BOL D'AIR, OXYGENATION AND FREE RADICALS

Béatrice Mercier, PhD in Life Sciences and Biochemistry of Cellular Oxygenation, has assembled a considerable bibliography on cellular oxygenation, the role of terpene essences and the benefits of the tetravalent form of oxygen generated by inhalations of the Jacquier Bol d’air.

Scientific observations, carried out at the University of Dijon, highlight the increase in the anti-radical capacity of organisms, in vivo and ex vivo. It is not a question of ingesting a specific anti-radical but of strengthening the body's overall reaction capacity to free radicals during Bol d'air inhalations.

As a result the method is both oxygenating and non-oxidising, whereas the increase in oxygen, commonly used in other methods, carries the risk of generating oxidative stress in the cell.

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BOL D'AIR, NUTRITION AND EXCESS WEIGHT

From 2003, Italian researchers, nutritionists, endocrinologists and clinicians, P. De Cristofaro, A. Pietrobelli and N.C. Battistini, communicated on the role of oxygenation in the field of obesity: their work, presented at the International Congress of San Diego USA (FASEB recognised), Helsinki Obesity Congress and World Obesity Congress of Prague, demonstrate that the use of the Bol d'air allows both to decrease body fat mass and to increase lean mass, significantly compared to a control group. Since then, the Bol d'air has been used in specialised centres in Italy, as a natural accompaniment and support for the treatment of obesity and metabolic conditions.

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BOL D'AIR AND HIGH-PERFORMANCE SPORT

Dr. Andrea Lino, sports medicine specialist, Professor of Human Physiology at La Sapienza University in Rome, observesthe remarkable effects of Bol d'air on explosive strength, muscular elasticity and endurance with swimmers.

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BOL D'AIR AND ENERGY

ESP consulting, an independent research laboratory, evaluates the effects of Bol d'air inhalations on healthy athletes. The impact on training is very significant in two groups on metabolic and respiratory adaptation criteria, with an improved trend for users of the Bol d'air, on at least three criteria:

- After 10 weeks of training, the maximum exercise ventilation increases by 2.5% for the control group and by 9.3% for the Bol d'air group.
- After this same period of time, the VO2 max decreases by 2.8% for the control group and increases by 5.5% for the Bol d’air group.
- The fatigue score decreases by 9.5% after training for the controls and by 36.6% for the Bol d'air group. This improvement demonstrates that the Bol d'air is a very important aid for recovery from exercise.

This is why athletes of all levels and from all walks of life incorporate the Bol d'air into their training.

BOL D'AIR AND CEREBRAL ACTIVITY

A new advance in research on the Jacquier Bol d’air has been developed thanks to a scientific team from Marseilles led by Professor Eric Sérée.

Under the effects of regular breathing sessions (3 min of Aero2, 5 times a week, for 5 months), certain genes present in the mammalian brain were activated. These genes allow the body to produce special proteins (sirtuins, particularly Sirt-1) of great interest for health and well-being.

These molecules intervene to fight against inflammatory processes, apoptosis (cellular self-destruction) oxidative stress and cellular aging as well as to improve resistance to stress and stimulate the creation of new mitochondria, these cellular energy centres being essential for the supply of energy. They are involved in the metabolism of cholesterol and could be protective against atheroma, the fight against plaque deposition.

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BOL D'AIR AND MITOCHONDRIAL HEALTH

It is possible to apprehend the state of mitochondrial health via the evaluation of the level of iso-enzymes. The study, involving 10 healthy or sick people, found thatthe breathing sessions of the Jacquier Bol d'air improved these markers in 8 out of 10 cases.

German study conducted in the office of Heilpraktiker Frank Stubenvoll.

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BOL D'AIR AND FATIGUE

A recent observational study by Dr. Horgue (March 2019) confirms that undergoing Bol d'air sessions reduces feelings of fatigue in people with hypermobile Ehlers Danlos syndrome (EDS or HSD – Hypermobility Spectrum Disorder).

Ehlers-Danlos syndrome (EDS), the most common hereditary connective tissue disease, requires treatment with medical oxygen therapy, for 20 minutes twice a day. Several people have agreed to compare this medical oxygenation to 3-minute breathing sessions of the Jacquier Bol d'air.
For approximately 30 people, practicing a 3 min session of Bol d'air during their visit to the doctor's office, an immediate, more effective and faster improvement in fatigue, than medical oxygenation was observed (about 2 points on a scale ranging from 1 to 10), over a time varying between 6 and 8 hours.
For approximately 6 patients, carrying out one to two sessions of Bol d'air per day for 10 days, the same rapid effect of improvement in fatigue was observed, with the addition of a reduction in migraines (approximately 2 points on an analog scale ranging from 1 to 10). In both cases, the breathing sessions were effective on breathing difficulties (shortness of breath).
Even if the sample of volunteers is too small to lead to a generalisation, these positive effects of the Bol d'air device on fatigue are interesting to take into account.

For more on EDS Syndrome: http://www.gersed.com/

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OBSERVATIONS ON THE USE OF THE BOL D'AIR

An aside in a medical environment, in follow-up care and rehabilitation for patients as well as for those accompanying them. The Bol d'air is real mediation tool’ which ‘is shared without moderation’.

- Patient satisfaction survey on the use of the Bol d'air in SSPI at the Clinique de l'Olivier. ‘No one was familiar with the method and all were impressed by the experience offered’. Results of the satisfaction survey - Use of the Jacquier Bol d'air in SSPI - June 2019.pdf.
- Impact of the Jacquier Bol d'air on post-operative nausea and vomiting: these very significant results have encouraged other teams and establishments to use the Bol d'air.

2016 BAJ AND NVPO DR ABOSSOLO EVALUATION

BOL D'AIR AND PROTEIN GLYCATION

A well-oxygenated cellular environment helps combat protein glycation.
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Turpentine essential oil

BIOLOGICAL IMPACTS OF TURPENTINE ESSENTIAL OIL

This work presents a summarised bibliography of the main biological impacts of the essential oil (EO) of turpentine, its origin and its use in traditional and modern medicine. More specifically, a synthesis is made of the medical, biological and environmental impacts of the major components of the most volatile part of EO (α - and β -pinenes), as well as its safety for human health.

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Cellular oxygenation

ANTI-RADICAL CAPACITY ASSESSMENT

Measurement of the impact of the lifestyle of healthy subjects by evaluating their overall antiradical capacity.
By Lesgards JF, Durand P, Lassarre M, Stocker P, Lesgards G, Lanteaume A, Prost M, Lehucher-Michel MP.
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HISTORY AND FUTURE VISION OF OXIDATIVE STRESS, HUMAN CONDITIONS AND SOD

The evolution of free radicals and oxidative stress.
By McCord JM, Edeas MA.
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WINTER AIR POLLUTION

Winter air pollution in relation to infantile bronchiolitis in Paris.
By Ségala C, Poizeau D, Mesbah M, Willems S, Maidenberg M.
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